The Milky Way swarms with orbiting satellite dwarf galaxies of astounding diversity. Some galaxies continue to form stars while others stop and dim in brightness. In computer simulations, the evolutionary history of each dwarf galaxy that leads to these differences is known. Galaxies can lose gas and stop forming stars due to early exposure to stellar radiation (reionization), interaction with the hot gas of the host (ram-pressure stripping), or gravitational interactions with the host/dwarf galaxies (tidal effects).
A central issue facing systems neuroscience is defining the rich naturalistic behavioral repertoire that mice engage in under psychiatrically relevant situations. Recent advances in deep learning (e.g., DeepLabCut) have made frame by frame detailed pose estimation possible. However, this dense behavioral data requires new techniques for defining the ethogram (full description of behavior). To date, researchers have used frequency based time series approaches to tackle this problem, with significant limitations. An alternative approach would be to take advantage of new topology methods (persistent homology and directed algebraic topology) to characterize the shapes formed by mouse limb trajectories. Such an approach would have broad application in systems neuroscience. For this project, the student will use machine learning to label animal body parts, then topology to characterize the ethogram and compare the results to existing approaches.